A method for automatically determining the ventilatory (or "anaerobic") threshold breakpoint for adaptive rate pacing without the need for directly measuring anaerobic threshold or ventilatory threshold comprises: (a) positioning a first sensing electrode in the heart or superior vena cava of a patient...http://www.google.com.hk/patents/US6411850?utm_source=gb-gplus-share專利 US6411850 - Method of determining a ventilatory threshold breakpoint for an adaptive rate pacemaker