The present invention provides a method for detecting a mutation in a nucleic acid molecule which comprises contacting the nucleic acid molecule with a probe. The probe comprises two covalently linked nucleic acid segments under conditions such that the unlinked end of each segment of the probe is capable...http://www.google.com.hk/patents/US20040229221?utm_source=gb-gplus-share專利 US20040229221 - Method to detect mutations in a nucleic acid using a hybridization-ligation procedure