A method and system for detecting and displaying clustered microcalcifications in a digital mammogram, wherein a single digital mammogram is first automatically cropped to a breast area sub-image which is then processed by means of an optimized Difference of Gaussians filter to enhance the appearance...http://www.google.com.hk/patents/US6167146?utm_source=gb-gplus-share專利 US6167146 - Method and system for segmentation and detection of microcalcifications from digital mammograms