搜尋 圖片 地圖 Play YouTube 新聞 Gmail 雲端硬碟 更多 »
進階專利搜尋 | 網頁紀錄 | 登入

專利

公開號US4928698 A
出版類型授權
申請書編號07/337,024
發佈日期1990年5月29日
申請日期1989年4月12日
優先權日期
1988年4月19日
其他公開專利號
發明人
原專利權人
美國專利分類號
國際專利分類號
合作分類
歐洲分類號
G01S15/58E
A61B8/06
參考文獻
外部連結
Device for measuring the speed of moving organs and blood flows by correlation
US 4928698 A
摘要

A device for measuring the speed of moving organs and blood flows, comprising an intercorrelation circuit (100) which supplies on the basis of two successive shifted echographic lines, 2I+1 correlation function values, and a multiplex/interpolation circuit (200) which supplies, on the basis of the correlation function values, an estimate of the speed and the value of the corresponding correlation peak. In accordance with the invention, the intercorrelation circuit (100) and multiplex/interpolation (200) circuit supply the estimate of the speed and the value of the correlation peak within each of N shift zones. On the other hand, the device also comprises a zero-crossing detector (300) which defines M segments which are limited by the values of the scanning depth for which the speed passes through zero in the set of N zones, a memory (400) storing the values P.sub.ij of the correlation peak corresponding to the i.sup.th zone (i=1, . . . , N) and the j.sup.th segment (j=1, . . . , M), a detector unit (500) reconstructing the speed profile searched by retaining for each segment j the speed profile in the zone i for which P.sub.ij is maximum.

聲明
I claim:

1. In an ultrasonic examination system for measuring the speed of moving organs and blood flows of the type responsive to an echographic signal representing recurrent emission with a recurrent period T comprising intercorrelation means which operates with a sampling step Δt which supplies on the basis of two successive echographic lines shifted by kΔt (k=-I, -I+1, . . . , I), 2I+1 correlation function values and multiplex/interpolation means which supplies, on the basis of correlation function values, a signal representing an estimate of the speed and the value manifested by the corresponding correlation peak, the improvement therewith comprising:

said intercorrelation means and multiplex means including means responsive to said echographic signal applied as an input thereto for generating an output signal having first and second values respectively manifesting an estimate of (1) the speed and (2) the value of the correlation peak within each of N zones defined in the time shift interval {-IΔt, +IΔt};

zero crossing detector means responsive to said output signal first value for generating a signal defining M segments limited by the values of the scanning depth for which the estimate of the speed passes through zero in the set of N zones;

memory means responsive to said output signal second value and to the zero crossing detector means generated signal for storing the accumulated values P.sub.ij of the correlation peak corresponding to the i.sup.th zone (i=1, . . . , N) and to the j.sup.th segment (j=1, . . . , M); and

detection means responsive to the stored accumulated values P.sub.ij for reconstructing the speed profile searched by retaining for each segment j the speed profile in the zone i for which P.sub.ij is maximum.

2. A device as claimed in claim 1, characterized in that said intercorrelation means comprises a plurality of 1-bit correlators responsive to said echographic signal for generating a correlation signal and in that said multiplex/interpolation means includes means responsive to said correlation signal for performing linear interpolation in generating said output signal.

說明

The invention relates to a device for measuring the speed of moving organs and blood flows, comprising an intercorrelation circuit which supplies correlation function values on the basis of two successive echographic lines, and a multiplex/interpolation circuit which supplies, on the basis of said correlation function values, an estimate of the speed and the value of the corresponding correlation peak.

The invention is particularly attractively used in the field of echographic examination of moving organs, such as the cardiac walls and blood flows in vessels.

The general technical problem to be solved by any device for measuring the speed of moving organs and blood flows is to obtain an exact as possible estimate of the axial speed of the movement being studied in order to form, using display devices, exact images of organs and blood flows subjected to an ultrasound echographic examination.

In recent years various solutions to this technical problem have been proposed. In this sense French patent application No. 2 590 790 (corresponding to U.S. Pat. No. 4,803,990 assigned to the assignee of the present invention) describes a device for measuring the speed of moving organs and blood flows of the kind set forth which utilises the fact that the ultrasound signals successively backscattered by a moving target are linked by the following equation in the case of recurrent emission with a recurrent period T:

S.sub.n+1 (t)=S.sub.n (t-τ)

This signifies that the signal n+1 is the replica of the preceding signal n, except for a time shift τ. The latter is the supplementary time necessary for the ultrasound wave to travel the path transducer-target-transducer from one emission to an other. In other words:

τ=2VT/C

where V is the speed of the target and C is the speed of sound. It appears that measurement of τ enables the desired measurement of the speed V.

The intercorrelation function between S.sub.n (t) and S.sub.n+1 (t) is defined by: ##EQU1## and verifies that

C.sub.n,n+1 (to+u)=C.sub.nn (to,u-τ)

The time to relates to the exploration depth z as to=2z/C.

The function C.sub.nn (to,u) is an autocorrelation function and, therefore, it is maximum for u=o. Thus, a measure of the time shift, and hence of the speed V, can be obtained by determining for which parameter u the function C.sub.n,n+1 (to,u) is maximum. To this end, the intercorrelation function is sampled with a sampling step Δt, between u.sub.min =-IΔt and u.sub.max =IΔt in steps of 1, in order to obtain 2I+1 correlation function values. The maximum value of these 2I+1 values corresponding to u=uo enables measurement of τ by using the equality τ=uo.

In order to remove the errors inherent of sampling during the determination of the maximum value of the correlation function, use can be made of a multiplex/interpolation circuit which supplies, on the basis of correlation function values, a more exact estimate of the speed and the value of the corresponding correlation peak. French patent application No. 2 590 790 discloses an example of such a type of echographic signal processing where the correlation between signals is a correlation which is referred to as a "1 bit" correlation in the sense that the previously used signals S.sub.n+1 and S.sub.n are reduced to the sign of the ultrasonic signal. It is known that in that case the peak of the correlation function has an isosceles triangular shape. Knowledge of this shape enables reconstruction on the basis of the highest point and its two neighbours, of the complete correlation peak by linear interpolation, thus enabling exact determination of the location of uo.

This known method for measuring speeds, based on analysis of the time shift, offers substantial advantages over other methods which are based, for example on frequency shift or phase shift. It notably enables the use of broadband emission signals, resulting in a good axial measuring resolution. Moreover, taking into account the fact that the method for measurement by correlation does not involve a folding phenomenon, speeds can still be measured beyond the threshold generally imposed by customary instruments.

However, the method disclosed above has the drawback that it may give rise to an error, related to the sampling, in the determination of the position of the correlation peak. Actually, it may occur that the highest point of the sampled correlation function does not belong to the searched correlation peak. This situation can occur when complex fluxes are measured, comprising substantial speed gradients which tend to lower the correlation peak. This error becomes manifest as abrupt discontinuities in the reconstruction of the speed profile V as a function of the scanning depth z.

Thus, the technical problem to be solved in accordance with the invention is to realise a device for measuring the speed of moving organs and blood flows which comprises an intercorrelation circuit which operates with a sampling step Δt and which supplies, on the basis of two successive echographic lines shifted by kΔt (k=-I, -I+1, . . . , I), 2I+1 correlation function values, and which also comprises a multiplex/interpolation circuit which supplies, on the basis of said correlation function values, an estimate of said speed and the value of the corresponding correlation peak, which device enables unambiguous determination of the position of the maximum of the correlation peak by eliminating the artefacts due to large speed gradients.

The solution to this technical problem in accordance with the present invention consists in that said intercorrelation circuit and multiplex/interpolation circuit supply said estimate of the speed and said value of the correlation peak within each of N zones defined in the time shift interval [-IΔt, +IΔt], in that it also comprises a zero-crossing detector which defines M segments which are limited by the values of the scanning depth for which the estimate of the speed passes through zero in the set of N zones, a memory storing the accumulated values P.sub.ij of the correlation peak corresponding to the i.sup.th zone (i=1, . . . , N) and to the j.sup.th segment (j=1, . . . , M), and in that a detector unit reconstructs the speed profile searched by retaining for each segment j the speed profile in the zone i for which P.sub.ij is maximum.

Thus, the invention essentially consists of the "following" of the correlation peak along all possible paths presented by the N zones and the M segments, the selection criterium being the accumulated value of the correlation peak in all patterns. The path retained is that which corresponds to the highest value.

The invention will be described in detail hereinafter with reference to the accompanying diagrammatic drawings.

FIG. 1 shows a diagram of the measuring device in accordance with the invention.

FIG. 2 shows a curve illustrating the correlation function as a function of sampling in the case of a 1-bit correlation, as well as the zone structure.

FIG. 3 shows, for each zone, the variations of the estimated speed as a function of the scanning depth, as well as the segment structure.

FIG. 4 shows an experimental result obtained by Applicant.

FIG. 5 shows the structure of the memory used for obtaining the result shown in FIG. 4.

FIG. 1 diagrammatically shows a device for measuring the speed of moving organs and blood flows. This device forms part of an apparatus for ultrasonic examination by echography which also comprises (not shown in FIG. 1) at least one ultrasonic transducer which is connected to a stage for the periodical transmission of a pulse signal having a given recurrent frequency F=1/T, and to a stage for receiving echographic signals returned to the transducer and for processing the signals received. French patent application No. 2 590 790 contains a detailed description of these stages. The receiving and processing stage notably comprises a delay line having a recurrent period T which enables the simultaneous reception of two consecutive echographic signals S.sub.n (t) and S.sub.n+1 (t). As appears from FIG. 1, these two signals S.sub.n and S.sub.n+1 are processed by an intercorrelation circuit 100 which operates with a sampling step Δt.

Delay lines 101.sub.k shift the signal S.sub.n (t) by an amount u.sub.k =kΔt, the integer k taking the values -I, -I+1, . . . , 1, 0, 1, . . . , I-1, I. Subsequently, correlators 102k numbering 2I+1 supply 2I+1 correlation function values, i.e.:

{C.sub.n,n+1 (to,u.sub.k)}kε[-I, I].

The correlators 102k may be, for example "1 bit" correlators. FIG. 2 shows the correlation function which, as appears, is in that case formed by correlation peaks having the shape of isosceles triangles. The curve of FIG. 2 corresponds to a value of the number I equal to 5, representing 11 correlation points. This situation occurs, for example, for a transmission frequency of 5 MHz and a sampling frequency of 20 MHz.

The set of 2I+1 correlation function values supplied by the intercorrelation circuit 100 is subsequently applied to a multiplex/interpolation circuit 200. This circuit 200 parts the correlation points by grouping these points in N zones Z.sub.i (i=1, . . . , N). FIG. 2 shows such a partitioning in three zones Z.sub.1, Z.sub.2 and Z.sub.3, each of which comprises three correlation points. Inside each zone Z.sub.1 the circuit 200 supplies signals whose values represent an estimate of the speed V.sub.i and of the correlation peak P.sub.i. These values being a function of the time to, and hence of the scanning depth, are referenced as V.sub.i (z) and P.sub.i (z). In the case of 1 bit correlation (FIG. 2) V.sub.i (z) and P.sub.i (z) can be calculated by linear interpolation on the highest point of each zone and its two neighbours, the summit of the isosceles triangle thus reconstructed corresponding to the couple V.sub.i (z), P.sub.i (z). This interpolation method is described in the aforementioned French patent application No. 2 590 790.

The N speed profiles V.sub.i (z) can be graphically represented as a function z as appears from FIG. 3. It will be evident from this Figure that the profiles V.sub.i (z) exhibit passages through zero, corresponding to the absence of the correlation peak in the zone Z.sub.i considered for example, for the zone Z.sub.2 in FIG. 2. The passages through zero Z.sub.1, Z.sub.2, . . . , Z.sub.j, . . . are detected by a zero-crossing detector 300 and enable definition of M segments Δj(j-1, . . . M) along the axis z. In the example shown in FIG. 3, the number of segments Δ.sub.1 -Δ.sub.j is M=7. The M segments Δ.sub.j thus being defined, within each of these segments for each zone Z.sub.i, the values P.sub.i (z) of the correlation peak can be accumulated so as to define a number P.sub.ij which can be written as: ##EQU2##

The N by a detection unit 500 as follows: for each segment Δ.sub.j it is checked for which zone Z.sub.i the parameter P.sub.ij is maximum. Thus, the portion of the total profile V(z) searched, within the segment Δ.sub.j, is exactly V.sub.i (z). The values V.sub.i (z) are stored in a memory, reconstruction being realised by successively searching these values until P.sub.ij is maximum. This can be translated by the relation: ##EQU3##

In the example experimentally obtained by Applicant and shown in FIG. 4, the memory 400 had the structure given in FIG. 5. It contained 3 for each segment Δ.sub.j are denoted by a cross. The profile V(z) searched is thus given by: V.sub.2 (z) for the segments Δ.sub.1, Δ.sub.2, subsequently by V.sub.1 (z) for Δ.sub.3, Δ.sub.4, Δ.sub.5 and finally again by V.sub.2 (z) for Δ.sub.6.

專利引用
引用的專利申請日期發佈日期 申請者專利名稱
US46807391985年4月4日1987年7月14日Cgr UltrasonicProcess for removing all ambiguity from the measurement by Doppler effect of the speed of a moving target
US48039901986年8月25日1989年2月14日U.S. Philips CorporationExamining moving objects by ultrasound echograpy
被以下專利引用
引用本專利申請日期發佈日期 申請者專利名稱
US50001841989年9月15日1991年3月19日U.S. Philips CorporationDirectional component measurement by echography
US50624301990年5月4日1991年11月5日U.S. Philips CorporationDevice for measuring the speed of blood flows by ultrasonic echography at an increased measuring speed
US50819941991年3月21日1992年1月21日Siemens AktiengesellschaftMethod and apparatus for avoiding ambiguities in a pulse doppler apparatus
US51038271990年12月14日1992年4月14日Medasonics, Inc.Apparatus for and a method of distinguishing ultrasound signals returned from bubbles and particles moving in a fluid from signals due to ultrasound transducer motion
US51974771990年10月12日1993年3月30日Advanced Technology Laboratories, Inc.Ultrasonic doppler flow measurement system with tissue motion discrimination
US53868301993年10月25日1995年2月7日Advanced Technology Laboratories, Inc.Ultrasonic pulsed doppler flow measurement system with two dimensional autocorrelation processing
US55446571994年9月9日1996年8月13日Siemens Medical Systems, Inc.Ultrasound blood flow monitor of the non-doppler type
US56091551995年4月26日1997年3月11日Acuson CorporationEnergy weighted parameter spatial/temporal filter
US56239301995年5月2日1997年4月29日Acuson CorporationUltrasound system for flow measurement
US56693861996年7月31日1997年9月23日Hewlett-Packard CompanyUltrasonic flow measurement system employing cross-correlation of baseband reflection data
US57182291996年5月30日1998年2月17日Advanced Technology Laboratories, Inc.Medical ultrasonic power motion imaging
US57249741996年3月22日1998年3月10日Acuson CorporationTwo-dimensional ultrasound display system
US57856551997年3月24日1998年7月28日Acuson CorporationTwo-dimensional ultrasound display system
US58609301997年3月10日1999年1月19日Acuson CorporationEnergy weighted parameter spatial/temporal filter
US58714471996年11月7日1999年2月16日Acuson CorporationDoppler energy-related parameters in an ultrasound imaging system
US58998641997年4月9日1999年5月4日Acuson CorporationAdaptive temporal filtering to enhance fluid flow or tissue motion imaging
US60303441997年8月22日2000年2月29日Acuson CorporationMethods and apparatus for ultrasound image quantification
US60660951998年5月13日2000年5月23日Duke UniversityUltrasound methods, systems, and computer program products for determining movement of biological tissues
US60931491999年7月23日2000年7月25日Acuson CorporationMethod and apparatus for setting the integration interval for time integrated surface integral in an ultrasound imaging system
US61101181999年2月4日2000年8月29日Acuson CorporationMethod and apparatus for ultrasound image quantification
US61779231996年10月25日2001年1月23日Acuson CorporationImaging modality showing energy and velocity
US61936641999年2月4日2001年2月27日Acuson CorporationMethod and apparatus for ultrasound image quantification
US62416772000年1月6日2001年6月5日Acuson CorporationMethod and apparatus for ultrasound image quantification
US63225112000年1月6日2001年11月27日Acuson CorporationMethods and apparatus for ultrasound image quantification
US64196322000年3月30日2002年7月16日Kabushiki Kaisha ToshibaHigh resolution flow imaging for ultrasound diagnosis
US64646402000年1月6日2002年10月15日Acuson CorporationMethods and apparatus for ultrasound imaging with automatic color image positioning
EP0481691A11991年10月11日1992年4月22日Advanced Technology Laboratories, Inc.Ultrasonic doppler flow measurement system with tissue motion discrimination