Sep 6, 2022 · Collectively, we reveal cross-talk between the AIM2 inflammasome/IL-1β and IL-6 trans-signaling axes for potential exploitation as a therapeutic ...
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Aug 29, 2022 · Furthermore, we discover that AIM2 is upregulated in emphysema by cross-talk with the immunomodulatory cytokine interleukin 6. These findings ...
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Mar 28, 2010 · The AIM2 inflammasome induces maturation of the proinflammatory cytokines IL-1β and IL-18. Using AIM2-deficient mice, Fitzgerald and ...
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May 22, 2021 · The AIM2 inflammasome is activated by the inappropriate presence of double-stranded DNA (dsDNA) in the cytosolic compartment due to transport by ...
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AIM2 ; Supply Voltage: 24 VAC (+/- 10%), 50/60 Hz ; Supply Current: 200 mA maximum ; Input Voltage Signal Preset Ranges: 0-5V, 0-10V, 0-15V, 0-20V, 1-5V, 2-10V, 3- ...
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May 19, 2023 · AIM2 is a bipartite protein consisting of an N-terminal pyrin domain (PYD), which coordinates homotypic binding to ASC, and a C-terminal HIN ...
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Sep 14, 2021 · AIM2 deficiency in B cells ameliorates systemic lupus erythematosus by regulating Blimp-1–Bcl-6 axis-mediated B-cell differentiation. Ming Yang, ...
Aug 7, 2023 · AIM2 is a proinflammatory protein which is a critical part of the inflammasome. LacZ is expressed from the targeted allele in thioglycolate- ...
Nov 17, 2023 · AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA ...
AIM2 is a cytosolic innate immune receptor which recognizes double-stranded DNA (dsDNA) released during cellular perturbation and pathogenic assault.