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The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen ...
T cell receptor (TCR) signaling in health and disease - Nature
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Dec 13, 2021 · TCR-mediated T cell activation involves both the canonical (classical) and the non-canonical (alternative) NF-κβ pathway. An essential factor ...
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Feb 15, 2023 · TCR-T and CAR-T cell therapies consist in genetically engineered T cells, modified to express a receptor directed against a tumor antigen. CAR-T ...
Jun 30, 2021 · T-cell receptor (TCR)-based adoptive therapy employs genetically modified lymphocytes that are directed against specific tumor markers.
The TCR (T-cell receptor) is a complex of integral membrane proteins that participate in the activation of T-cells in response to an antigen. Stimulation of TCR ...