Feb 10, 2017 · Megakaryocytic microparticles (MkMPs), the most abundant MPs in circulation, can induce the differentiation of hematopoietic stem and ...
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Mar 4, 2021 · Intriguingly, we identified a subpopulation of CD42b+CD14+ MKs in vivo that exhibit high expression of genes associated with immune responses ...
Aug 27, 2015 · S1 Fig: Schematic outline of steps from 3D cell culture, MK differentiation, mature MK extraction from hydrogels and perfusion, and platelet ...
Runx1 downregulates cell-adhesion factors that promote residency of stem cells and megakaryocytes in their bone marrow niche. Abstract. Disrupting mutations of ...
Apr 7, 2016 · The production of megakaryocytes (MKs)—the precursors of blood platelets—from human pluripotent stem cells (hPSCs) offers exciting clinical ...
Dec 18, 2020 · Despite our growing understanding of embryonic immune development, rare early megakaryocytes (MKs) remain relatively understudied.
Apr 13, 2015 · The aim of this paper was to first review known key concepts about megakaryopoiesis and second to describe efforts done in our laboratory and ...
May 2, 2019 · New advances in interrogating hematopoiesis have revealed the presence of a megakaryocyte-biased hematopoietic stem cell which may differentiate ...